ErbB Signalling is a Potential Therapeutic Target for Vascular Lesions with Fibrous Component
H. Ilmonen, S. Jauhiainen, P. Vuola, H. Rasinkangas, H. H. Pulkkinen, S. Keränen, M. Kiema, J. J. Liikkanen, N. Laham-Karam, S. Laidinen, E. Aavik, K. Lappalainen, J. Lohi, J. Aronniemi, T. Örd, , J. P. Laakkonen
This study identifies ErbB signaling as a therapeutic target for vascular lesions with fibrous components by showing TGFA/VEGF-A paracrine signaling and the effect of PIK3CA mutations.
bioRxiv · Sep 23, 2022 · PreprintCell Biology