J. B. Edel

Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy

This study uses FLIM and a fluorescent probe to visualize G4 structures in live cells and assesses their stability and resolution by small molecule interactions.

Single-molecule nanopore sensing of actin dynamics and drug binding

This study uses nanopore sensing to analyze actin dynamics and drug binding in native, unmodified actin molecules, revealing transitional states and binding stoichiometries.