Deep learning-assisted single-molecule detection of protein post-translational modifications with a biological nanopore
C. Cao, P. Magalhaes, L. Krapp, J. Bada Juarez, S. Mayer, V. Rukes, A. Chiki, H. Lashuel, M. Dal Peraro
This study uses a biological nanopore and deep learning to detect and distinguish single and multiple PTMs on -synuclein peptides at picomolar concentrations.
bioRxiv · Sep 8, 2023Biophysics