Author

H. Lashuel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Chiki· 2 shared N. Riguet· 2 shared A. AlOkda· 1 shared B. Frey· 1 shared C. Cao· 1 shared D. Eliezer· 1 shared G. Limorenko· 1 shared J. A. Duce· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

A. Chiki

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Deep learning-assisted single-molecule detection of protein post-translational modifications with a biological nanopore

C. Cao, P. Magalhaes, L. Krapp, J. Bada Juarez, S. Mayer, V. Rukes, A. Chiki, H. Lashuel, M. Dal Peraro

This study uses a biological nanopore and deep learning to detect and distinguish single and multiple PTMs on -synuclein peptides at picomolar concentrations.

bioRxiv · Sep 8, 2023Biophysics

Non-monotonic fibril surface occlusion by GFP tags from coarse-grained molecular simulations

J. C. Shillcock, J. Hastings, N. Riguet, H. Lashuel

This study shows that GFP tags on amyloid fibrils create a non-monotonic sieve effect, altering their interactome and growth dynamics through coarse-grained simulations.

bioRxiv · Oct 21, 2021Biophysics

Monitoring alpha-synuclein oligomerization and aggregation using bimolecular fluorescence complementation assays: What you see is not always what you get.

B. Frey, A. AlOkda, M. P. Jackson, N. Riguet, J. A. Duce, H. Lashuel

This study evaluates the reliability of BiFC assays for monitoring alpha-synuclein oligomerization, finding that fluorescent signals do not accurately reflect oligomerization or aggregation.

bioRxiv · May 2, 2020Biochemistry

Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau

N. Ait-Bouziad, A. Chiki, G. Limorenko, S. Xiao, D. Eliezer, H. Lashuel

This study shows that phosphorylation of tyrosine 310 in Tau reduces its aggregation and microtubule/lipid-binding properties by decreasing β-sheet propensity in the PHF6 domain.

bioRxiv · Jan 6, 2020Biochemistry