Structural and Functional Consequences of Age-Related Isomerization in α Crystallins
Y. Lyon, D. Riggs, M. Collier, M. Degiacomi, J. Benesch, R. Julian
This study investigates how isomerization of amino acids in α- and β-crystallins affects protein assembly and function, showing significant disruptions in oligomerization and phosphorylation.
bioRxiv · Jul 9, 2018Biochemistry