Loss of mitochondrial localization of human FANCG causes defective FANCJ helicase
S. S. Mukhopadhyay, J. C. B. K, B. S. Kapoor, K. Mandal, S. Ghosh, R. B. Mokhamatam, S. K. Manna
This study shows that a mutation in FANCG causes loss of mitochondrial localization, leading to mitochondrial instability and impaired DNA repair.
bioRxiv · Jan 15, 2020Cancer Biology