Author

J. C. Cheung

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

H. Wang· 1 shared J. Jiang· 1 shared M. Gellert· 1 shared N. d. Val· 1 shared T. Fox· 1 shared W. Yang· 1 shared X. Chen· 1 shared X. Xu· 1 shared

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2020-2020 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

H. Wang

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1 paper

Recent·Most cited

Stretch and Twist of HEAT Repeats Leads to Activation of DNA-PK Kinase

X. Chen, X. Xu, Y. Chen, J. C. Cheung, H. Wang, J. Jiang, N. d. Val, T. Fox, M. Gellert, W. Yang

The paper reports cryoEM structures of DNA-PKcs in inactive and activated forms, revealing structural changes in HEAT repeats that drive kinase activation.

bioRxiv · Oct 19, 2020Biochemistry