Author

J. Calle-Espinosa

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

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E. V. Koonin· 1 shared G. Gruenhagen· 1 shared J. Iranzo· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

E. V. Koonin

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1 paper

Recent·Most cited

Cancer BiologybioRxivJan 10, 2022

Pervasive conditional selection of driver mutations and modular epistasis networks in cancer

J. Iranzo, G. Gruenhagen, J. Calle-Espinosa, E. V. Koonin

The paper develops Coselens to quantify conditional selection of driver mutations in cancer, identifying 296 conditionally selected gene pairs across 16 cancer types and revealing modular epistasis networks.

DOI 10.1016/j.celrep.2022.111272

humanwhole-genome sequencing

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