Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment.
A. Moussy, J. Cosette, R. Parmentier, C. da Silva, G. Corre, A. Richard, O. Gandrillon, D. Stockholm, A. Paldi
The paper integrates single-cell transcriptional data with time-lapse microscopy to show dynamic and variable hematopoietic cell fate commitment, revealing non-binary lineage decisions.
bioRxiv · Jan 18, 2017Cell Biology