J. Deretic

The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule nucleation and organization

This study identifies CCDC66 as a regulator of mitotic progression and cytokinesis by promoting microtubule nucleation and organization through interactions with centrosomal and noncentrosomal pathways.

CCDC66 regulates primary cilium length and signaling competence via multi-site interactions with transition zone and axonemal proteins

ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium assembly and Hedgehog signaling

This study identifies ENKD1 as a centriolar and ciliary microtubule-associated protein that regulates primary cilium assembly and Hedgehog signaling.