Author

J. Dessolin

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Larijani· 1 shared G. De Las Heras· 1 shared J. Requejo-Isidro· 1 shared R. Bailly· 1 shared V. Calleja· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

B. Larijani

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1 paper

Recent·Most cited

A Complex Interplay of Anionic Phospholipid Binding Regulates 3-Phosphoinositide-Dependent-Kinase-1 Homodimer Activation

G. De Las Heras, V. Calleja, R. Bailly, J. Dessolin, J. Requejo-Isidro, B. Larijani

This study reveals how anionic phospholipids regulate PDK1 homodimer activation through conformational dynamics, showing phosphatidylserine maintains inactivity and dysregulation leads to constitutive activation in carcinomas.

bioRxiv · Mar 3, 2019Biophysics