Author

J. E. Henley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Sell· 2 shared G. L. Rogers· 1 shared G. N. Llewellyn· 1 shared H.-Y. Chen· 1 shared L. Comai· 1 shared P. M. Cannon· 1 shared X. Huang· 1 shared Y. Yicheng He· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

P. Sell

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Author profile →

2 papers

Recent·Most cited

Differential outcomes of infection by wild-type SARS-CoV-2 and the B.1.617.2 and B.1.1.529 variants of concern in K18-hACE2 transgenic mice

Y. Yicheng He, J. E. Henley, P. Sell, L. Comai

This study compares the infectivity and inflammatory responses of SARS-CoV-2 wild-type, Delta, and Omicron variants in K18-hACE2 mice, finding differential viral RNA levels and inflammatory marker expression in lung, brain, and olfactory bulb tissues.

bioRxiv · Sep 8, 2023 · PreprintMicrobiology

Comparison of SARS-CoV-2 entry inhibitors based on ACE2 receptor or engineered Spike-binding peptides

G. N. Llewellyn, H.-Y. Chen, G. L. Rogers, X. Huang, P. Sell, J. E. Henley, P. M. Cannon

This study compares ACE2-derived and engineered Spike-binding peptide entry inhibitors against SARS-CoV-2 variants, finding that an optimized ACE2 derivative neutralizes all tested variants, while peptides show variable efficacy with resistance observed in Beta, Gamma, and Omicron variants.

bioRxiv · Jan 5, 2023 · PreprintMicrobiology