Impacts of Fluorescent Base Analogue Substitution on the Folding of a Riboswitch
J. E. Hoeher, N. E. Sande, J. R. Widom
This study investigates how inserting 2-AP into a preQ1 riboswitch affects its ligand binding and structure, finding that proximity to the ligand-binding pocket has the greatest impact.
bioRxiv · Jul 22, 2021Biochemistry