Author

J. R. Widom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Approach:simulation· 1

Frequent Co-Authors

C. L. Brooks· 1 shared D. R. Wonderlick· 1 shared I. Artsimovitch· 1 shared J. E. Hoeher· 1 shared M. J. Harms· 1 shared N. E. Sande· 1 shared N. G. Walter· 1 shared R. Hayes· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBiophysics

C. L. Brooks

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Author profile →

3 papers

Recent·Most cited

Disentangling contact and ensemble epistasis in a riboswitch

D. R. Wonderlick, J. R. Widom, M. J. Harms

The paper investigates contact and ensemble epistasis in an RNA riboswitch by analyzing mutation effects across different allosteric effector concentrations, finding both mechanisms contribute to epistasis.

bioRxiv · Oct 27, 2022Biophysics

Impacts of Fluorescent Base Analogue Substitution on the Folding of a Riboswitch

J. E. Hoeher, N. E. Sande, J. R. Widom

This study investigates how inserting 2-AP into a preQ1 riboswitch affects its ligand binding and structure, finding that proximity to the ligand-binding pocket has the greatest impact.

bioRxiv · Jul 22, 2021Biochemistry

Ligand Modulates Cross-Coupling between Riboswitch Folding and Transcriptional Pausing

J. R. Widom, Y. A. Nedialkov, V. Rai, R. Hayes, C. L. Brooks, I. Artsimovitch, N. G. Walter

The paper investigates how ligand binding affects the interaction between riboswitch folding and transcriptional pausing in bacterial RNA polymerase.

bioRxiv · Jun 19, 2018Biophysics