An RNA interference (RNAi) toolkit and its utility for functional genetic analysis of Leishmania ( Viannia )
L.-F. Lye, K. L. Owens, S. Jang, J. E. Marcus, E. A. Brettmann, S. M. Beverley
This study develops and applies RNAi tools to Leishmania (Viannia) species, showing that RNAi efficacy increases with stem length and enables hypomorphic analysis of essential genes.
bioRxiv · Nov 14, 2022 · PreprintMicrobiology