Generation of dual specific bivalent BiTEs (dbBIspecific T-cell Engaging antibodies) for cellular immunotherapy
M. Kujawski, L. Li, S. Bhatacharya, P. Wong, W.-H. Lee, L. (Obrien) Williams, H. Li, J. Cheah, K. Poku, N. Bowles, N. Vaidehi, P. Yazaki, J. E. Shively
This paper describes the generation of dual-specific bivalent BiTES for cancer immunotherapy, showing they maintain tumor targeting and kill CEA+ cells in vitro and in vivo.
BMC Cancer · Dec 1, 2019Peer-reviewedCancer Biology