Author

J. E. Speer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

L. A. Setton· 2 shared L. Jing· 2 shared M. N. Barcellona· 2 shared D. S. Patil· 1 shared F. Lee· 1 shared G. Easson· 1 shared J. J. Stivers· 1 shared J. M. Buchowski· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

L. A. Setton

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Author profile →

2 papers

Recent·Most cited

Single Cell RNA-Sequence Analyses Reveal Uniquely Expressed Genes and Heterogeneous Immune Cell Involvement in the Rat Model of Intervertebral Disc Degeneration

M. Rohanifar, S. W. Clayton, G. Easson, D. S. Patil, F. Lee, L. Jing, M. N. Barcellona, J. E. Speer, J. J. Stivers, S. Y. Tang, L. A. Setton

This study uses single-cell RNA-sequencing to identify immune cell infiltration and gene expression changes in rat intervertebral disc degeneration.

bioRxiv · Jul 5, 2022 · PreprintCell Biology

Engineered Peptide-Functionalized Hydrogels Modulate the RNA Transcriptome of Human Nucleus Pulposus Cells In Vitro

M. N. Barcellona, J. E. Speer, L. Jing, M. C. Gupta, J. M. Buchowski, M. P. Kelly, L. A. Setton

This study shows that LMP-functionalized hydrogels alter the transcriptome of human NP cells, upregulating NP markers and downregulating fibroblastic markers, and affecting multiple biological pathways.

bioRxiv · Mar 5, 2021 · PreprintCell Biology