Author

L. Jing

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 2 Immunology· 2 Biochemistry· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Organism:mouse· 2

Frequent Co-Authors

D. M. Koelle· 2 shared E. H. Warren· 2 shared J. E. Speer· 2 shared L. A. Setton· 2 shared M. N. Barcellona· 2 shared A. J. Minnaard· 1 shared A. M. H. Towlerton· 1 shared A. T. Jin· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersImmunology

D. M. Koelle

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

The progression of neurovascular features and chemokine signatures of the intervertebral disc with degeneration

Remy E. Walk, Kaitlyn S. Broz, L. Jing, Ryan P. Potter, C. E. Gonzalez, Alec T Beeve, Erica L. Scheller, M.C. Gupta, Lori A. Setton, S. Y. Tang

This study tracks the temporal changes in chemokine production and neurovascular invasion in mouse intervertebral discs during degeneration following injury.

European Cells and Materials · Dec 31, 2025Peer-reviewedBioengineering

T-cells specific for KSHV and HIV migrate to Kaposi sarcoma tumors and persist over time

S. Ravishankar, A. M. H. Towlerton, I. L. Tiamiyu, P. Mooka, J. Nankoma, J. Kafeero, D. Mubiru, S. Sekitene, L. D. Aicher, C. P. Miller, D. G. Coffey, L. Okoche, P. Atwinirembabazi, J. Okonye, J. White, , E. H. Warren

The paper identifies KSHV- and HIV-specific T-cells in KS tumors and shows they persist over time and coexist with immunosuppressive macrophages.

bioRxiv · Feb 6, 2024 · PreprintImmunology

Thermo-Responsive Polymers Targeting Inflammation in Murine Colitis

S. Zhang, A. T. Jin, W. Tang, R. Y. Zhang, L. Jing, Y. Zhou, H. Zhang, J. K. Lennerz, J. R. Korzenik, R. Langer, G. Traverso

This study develops thermo-responsive hydrogels that target inflamed colon mucosa for IBD treatment by exploiting charge-mediated interactions and thermo-responsiveness.

bioRxiv · Dec 28, 2023 · PreprintBioengineering

Epigenetic Reshaping through Damage: Promoting Cell Fate Transition by BrdU and IdU Incorporation

C. Li, S. Chen, X. Xu, T. Guan, A. Xu, C. Li, S. Yu, H. Wu, D. Pei, L. Jing

The paper investigates how BrdU and IdU incorporation through DNA damage repair induces epigenetic changes that promote cell fate transition.

bioRxiv · Aug 28, 2023Cell Biology

Single Cell RNA-Sequence Analyses Reveal Uniquely Expressed Genes and Heterogeneous Immune Cell Involvement in the Rat Model of Intervertebral Disc Degeneration

M. Rohanifar, S. W. Clayton, G. Easson, D. S. Patil, F. Lee, L. Jing, M. N. Barcellona, J. E. Speer, J. J. Stivers, S. Y. Tang, L. A. Setton

This study uses single-cell RNA-sequencing to identify immune cell infiltration and gene expression changes in rat intervertebral disc degeneration.

bioRxiv · Jul 5, 2022 · PreprintCell Biology

Engineered Peptide-Functionalized Hydrogels Modulate the RNA Transcriptome of Human Nucleus Pulposus Cells In Vitro

M. N. Barcellona, J. E. Speer, L. Jing, M. C. Gupta, J. M. Buchowski, M. P. Kelly, L. A. Setton

This study shows that LMP-functionalized hydrogels alter the transcriptome of human NP cells, upregulating NP markers and downregulating fibroblastic markers, and affecting multiple biological pathways.

bioRxiv · Mar 5, 2021 · PreprintCell Biology

CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells.

C. A. James, Y. Xu, M. S. Aguilar, L. Jing, E. D. Layton, M. Gilleron, A. J. Minnaard, T. Scriba, C. L. Day, E. H. Warren, D. M. Koelle, C. Seshadri

This study investigates how CD4 and CD8 co-receptors affect the functional avidity and activation of CD1b-restricted T cells specific for mycobacterial lipid antigens, revealing distinct functional profiles and proliferation patterns.

bioRxiv · Oct 17, 2020Immunology

Synergism of gut microbiota to double-stranded RNAs in RNA interference of a leaf beetle

L. Xu, S. Xu, L. Sun, Y. Zhang, L. Jing, R. Bock, J. Zhang

This study shows gut bacteria enhance dsRNA-induced mortality in leaf beetles by accelerating dsRNA degradation and causing microbiota dysbiosis.

bioRxiv · Oct 31, 2019 · PreprintEcology

Structure determination from lipidic cubic phase embedded microcrystals by MicroED

L. Zhu, G. Bu, L. Jing, D. Shi, T. Gonen, W. Liu, B. L. Nannenga

This study demonstrates the use of modified LCP and MicroED protocols to determine structures from microcrystals embedded in LCP using proteinase K as a model system.

bioRxiv · Aug 4, 2019Biochemistry