CHRONIC INFLAMMATION IN ULCERATIVE COLITIS CAUSES LONG TERM CHANGES IN GOBLETCELL FUNCTION
V. Singh, K. Johnson, J. Yin, S. Lee, R.-X. Lin, H. Yu, J. In, J. F. Abel, N. Zachos
This study shows that UC colonoids have persistent defects in mucus secretion despite reduced GC numbers, suggesting long-term epithelial dysfunction contributes to UC recurrence.
bioRxiv · Mar 17, 2021Physiology