Intranasal Administration of ACIS KEPTIDE™ Prevents SARS-CoV2-Induced Acute Toxicity in K18-hACE2 Humanized Mouse Model of COVID-19: A Mechanistic Insight for the Prophylactic Role of KEPTIDE™ in COVID-19
G. Gottschalk, J. F. Keating, K. Kesler, K. Knox, A. Roy
This paper shows that ACIS KEPTIDE prevents SARS-CoV2-induced toxicity and mortality in mice by reducing ACE-2 expression and viral entry.
bioRxiv · Nov 13, 2020 · PreprintAnimal Behavior & Cognition