Combined effects of matrix stiffness and obesity-associated signaling directs progressive phenotype in PANC-1 pancreatic cancer cells in vitro
A. E. Jones, J. F. Netto, T. L. Foote, Brian N. K. Ruliffson, Catherine F. Whittington
This study investigates how matrix stiffness and obesity-associated signaling influence PANC-1 pancreatic cancer cell behavior in vitro, showing increased invasiveness and amoeboid morphology under combined conditions.
bioRxiv · Jun 11, 2024 · PreprintBioengineering