Integration of Osteoclastogenesis through addition of PBMCs in Human Osteochondral Explants cultured Ex vivo
E. E. A. Cramer, B. M. W. de Wildt, J. G. E. Hendriks, K. Ito, S. Hofmann
This study shows that adding PBMCs to human osteochondral explants enhances osteoclast activity and resorption, suggesting the need for external osteoclast precursors in long-term bone remodeling cultures.
bioRxiv · Aug 8, 2023 · PreprintCell Biology