Development of nanobodies as theranostic agents against CMY-2-like class C β-lactamases
F. Cawez, P. S. Mercuri, F. M. Yanez, R. Maalouf, M. Vandevenne, F. Kerff, V. Guerin, J. G. Mainil, D. Thiry, M. Salmon, A. Vanderplasschen, P. Lafaye, G. Ayme, P. Bogaerts, M. Dumoulin, M. Galleni
This study identifies VHH nanobodies that inhibit CMY-2 class C β-lactamases and develops an ELISA for detecting these enzymes in resistant bacteria.
bioRxiv · Jul 1, 2022 · PreprintBiochemistry