Detection of low-density Plasmodium falciparum infections using amplicon deep sequencing
A. M. Early, R. F. Daniels, T. M. Farrell, J. Grimsby, S. K. Volkman, D. F. Wirth, B. L. MacInnis, D. E. Neafsey
This paper evaluates four amplicon sequencing tools for detecting low-density Plasmodium falciparum infections, finding they can detect down to 5 genomes/l but have reduced accuracy at very low parasitemia.
bioRxiv · Feb 19, 2019Microbiology