Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2
J. Arizti-Sanz, C. A. Freije, A. C. Stanton, C. K. Boehm, B. A. Petros, S. Siddiqui, B. M. Shaw, G. Adams, T.-S. F. Kosoko-Thoroddsen, M. E. Kemball, R. Gross, L. Wronka, K. Caviness, L. E. Hensley, N. H. Bergman, , C. Myhrvold
This paper develops SHINE, a diagnostic tool for SARS-CoV-2 detection with 90% sensitivity and 100% specificity, reducing contamination risk and enabling use outside clinical settings.
bioRxiv · May 28, 2020 · PreprintBioengineering