J. H. Cole

Heterogeneous Tissue Modulus Improved Prediction of Mechanical Behavior in Osteoporotic Vertebral Cancellous Bone

This study shows that using specimen-specific heterogeneous tissue modulus improves predictions of mechanical behavior in osteoporotic vertebral cancellous bone compared to uniform or average modulus models.

Changes in Cellular Crosstalk between Skeletal Muscle Myoblasts and Bone Osteoblasts with Aging

This study investigates how aging affects biochemical interactions between bone and muscle cells using a rat model, finding that co-culture promotes differentiation but does not alter age-related changes in IGF-1 or collagen expression.

Forelimb unloading impairs glenohumeral muscle development in growing rats

This study shows that forelimb unloading in growing rats impairs glenohumeral muscle development, with forearm amputation having greater effects than forelimb suspension.

Characterizing Trabecular Bone Properties near the Glenohumeral Joint Following Brachial Plexus Birth Injury

This study examines trabecular bone changes in a mouse model of brachial plexus birth injury, finding greater structural and mineralization impairments near the glenohumeral joint articulating surface.

Ischemic Stroke Reduces Bone Perfusion and Alters Osteovascular Structure

This study examines how ischemic stroke affects osteovascular structure and function in mice, finding increased osteovascular volume and altered vessel proximity to bone, with exercise exacerbating some effects.

High Fat Diet-Induced Obesity Negatively Affects Whole Bone Bending Strength but not Cortical Structure in the Femur

This study shows that high fat diet reduces femur bending strength and cancellous bone microstructure without affecting cortical structure or osteovascular properties.

A Minimally Invasive Technique for Serial Intraosseous Perfusion Measurements in the Murine Tibia Using Laser Doppler Flowmetry

This paper introduces a modified laser Doppler flowmetry technique to measure intraosseous perfusion in murine tibiae weekly without causing inflammation or gait abnormalities.

Validating Minimally Invasive Laser Doppler Flowmetry for Serial Bone Perfusion Measurements in Mice

This study validates a minimally invasive laser Doppler flowmetry technique for serial bone perfusion measurements in mice without causing inflammation or gait perturbations.

Stroke prevents exercise-induced gains in bone microstructure but not composition in mice

This study shows that stroke inhibits exercise-induced gains in femoral microstructure but not tibial composition in mice, even without bedrest.