Author

H. Sheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Microbiology· 2 Cancer Biology· 1 Pathology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:development & morphogenesis· 4 Research Focus:differential expression· 4 Assay:imaging· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

A. J. Steward· 2 shared F. Wang· 2 shared H. L. Thornburg· 2 shared J. H. Cole· 2 shared N. J. Hanne· 2 shared Y. Li· 2 shared Y. Zhang· 2 shared Y. Zhou· 2 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBioengineering

A. J. Steward

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A Deep Learning Approach for Histology-Based Nuclei Segmentation and Tumor Microenvironment Characterization

R. Rong, H. Sheng, K. W. Jin, F. Wu, D. Luo, Z. Wen, C. Tang, D. M. Yang, L. Jia, M. Amgad, L. A. D. Cooper, Y. Xie, X. Zhan, S. Wang, G. Xiao

This study introduces HD-Yolo, a deep learning method for faster and more accurate nuclei segmentation and tumor microenvironment quantification in whole-slide images.

bioRxiv · Dec 8, 2022 · PreprintPathology

Multi-Molecular Hyperspectral PRM-SRS Imaging

L. Shi, W. Zhang, Y. Li, A. A. Fung, Z. Li, H. Jang, H. Zha, X. Chen, F. Gao, J. Y. Wu, H. Sheng, J. Yao, D. Skowronska-Krawczyk, S. Jain

The paper introduces PRM-SRS imaging to visualize and identify multiple lipid species in cells and tissues with high chemical specificity and subcellular resolution.

bioRxiv · Jul 25, 2022 · PreprintBioengineering

COVID-ONE-humoral immune: The One-stop Database for COVID-19-specific Antibody Responses and Clinical Parameters

Z. Xu, Y. Li, Q. Lei, L. Huang, D.-y. Lai, S.-j. Guo, H.-w. Jiang, H. Hou, Y.-x. Zheng, X.-n. Wang, J. Wu, M.-l. Ma, B. Zhang, H. Chen, C. Yu, , S.-c. Tao

The paper introduces a database that compiles antibody responses and clinical data from COVID-19 patients for analysis and visualization.

bioRxiv · Jul 29, 2021 · PreprintMicrobiology

Human fecal microbiota is associated with colorectal cancer

Q. Yao, M. Tang, L. Zeng, Z. Chu, H. Sheng, Y. Zhang, Y. Zhou, H. Zhang, H. Jiang, M. Ye

This study analyzes fecal microbiota composition in CRC patients and identifies Fusobacterium as a potential biomarker for CRC screening in Chinese populations.

bioRxiv · Nov 17, 2020 · PreprintMicrobiology

Systematic analysis of aberrances of ferroptosis reveals its potential functional roles in cancer

Z. Liu, Q. Zhao, Z. Zuo, S.-Q. Yuan, K. Yu, Q. Zhang, X. Zhang, H. Sheng, H.-Q. Ju, H. Cheng, F. Wang, R.-H. Xu, Z.-X. Liu

This study systematically analyzes ferroptosis in cancer using TCGA data, finding that ferroptosis-related genes are aberrantly expressed and that FPI is associated with prognosis and drug sensitivity.

bioRxiv · Apr 19, 2020Cancer Biology

YSL3-mediated copper distribution is required for fertility, grain yield, and size in Brachypodium.

H. Sheng, Y. Jiang, M. Rahmati Ishka, J.-C. Chia, T. Dokuchayeva, Y. Kavulych, T.-O. Zavodna, P. N. Mendoza, R. Huang, L. M. Smieshka, A. R. Woll, O. I. Terek, N. D. Romanyuk, Y. Zhou, O. K. Vatamaniuk

This study identifies YSL3-mediated copper transport as critical for fertility, grain yield, and size in Brachypodium, with implications for improving crop production in copper-deficient soils.

bioRxiv · Dec 12, 2019 · PreprintPlant Biology

Ischemic Stroke Reduces Bone Perfusion and Alters Osteovascular Structure

N. J. Hanne, A. J. Steward, C. Geeroms, E. D. Easter, H. L. Thornburg, G. Kerckhofs, T. Parac-Vogt, H. Sheng, J. H. Cole

This study examines how ischemic stroke affects osteovascular structure and function in mice, finding increased osteovascular volume and altered vessel proximity to bone, with exercise exacerbating some effects.

bioRxiv · Aug 14, 2019Bioengineering

Stroke prevents exercise-induced gains in bone microstructure but not composition in mice

N. J. Hanne, A. J. Steward, M. R. Sessions, H. L. Thornburg, H. Sheng, J. H. Cole

This study shows that stroke inhibits exercise-induced gains in femoral microstructure but not tibial composition in mice, even without bedrest.

bioRxiv · Jul 19, 2019Bioengineering

Cyborg Organoids: Implantation of Nanoelectronics via Organogenesis for Tissue-Wide Electrophysiology

Q. Li, K. Nan, P. Le Floch, Z. Lin, H. Sheng, J. Liu

This paper introduces cyborg organoids with embedded nanoelectronics that monitor electrophysiology during organogenesis in human cardiac organoids.

bioRxiv · Jul 10, 2019Bioengineering