Author

J. H. Lewis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:fluorescence / live-cell microscopy· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Y. Zhou· 2 shared Z. Lu· 2 shared

Activity by Year

2022-2022 · peak 2/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersBiophysics

Y. Zhou

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2 papers

Recent·Most cited

Tracking multiple conformations occurring on angstrom-and-millisecond scales in single amino-acid-transporter molecules

Y. Zhou, J. H. Lewis, Z. Lu

The paper resolves four conformations of the AdiC transporter and quantifies their probabilities using polarization-microscopy, showing comparable KD values to prior methods.

bioRxiv · Jul 29, 2022Biophysics

Integrative 4D-conformational mechanisms of single AdiC transporter molecules

Y. Zhou, J. H. Lewis, Z. Lu

The paper uses polarization microscopy to determine the conformational dynamics of AdiC transporter molecules and builds a 4D model of its transport mechanism.

bioRxiv · Jul 29, 2022 · PreprintBiophysics