Cell BiologybioRxiv
Discovery of the sEH Inhibitor Epoxykynin as Potent Kynurenine Pathway Modulator
L. Doetsch, C. Davies, E. Hennes…·H. Waldmann
The paper identifies epoxykynin as a potent sEH inhibitor that modulates the kynurenine pathway, offering new opportunities to address cancer-induced immune tolerance.
DOI 10.1021/acs.jmedchem.3c02245