Dual effects of the small-conductance Ca2+-activated K+ current on human atrial electrophysiology and Ca2+-driven arrhythmogenesis: an in silico study
N. T. Herrera, X. Zhang, H. Ni, M. M. Maleckar, J. Heijman, D. Dobrev, E. Grandi, S. Morotti
This study uses in silico models to show that modulating the SK current in human atrial myocytes can both promote and prevent arrhythmias depending on the underlying mechanism.
bioRxiv · Jun 16, 2023Physiology