M. M. Maleckar

This study uses in silico models to show that modulating the SK current in human atrial myocytes can both promote and prevent arrhythmias depending on the underlying mechanism.

The paper improves computational methods to identify drug responses in mature human stem cell-derived cardiomyocytes using optical measurements and mathematical modeling.

DLITE infers cell-cell tensions from interface movement, showing better correlation with ground truth than prior methods and detecting tension changes during mitosis.

This paper presents a label-free method to predict 3D fluorescence images from transmitted light microscopy and shows it can generate integrated multi-structure images.