J. Hermisson

A theory of oligogenic adaptation of a quantitative trait

The paper develops an analytical framework to model phenotypic adaptation as a balance between monogenic and polygenic processes, showing that oligogenic adaptation is predicted by a population-scaled mutation rate parameter.

Modeling the genetic footprint of fluctuating balancing selection: From the local to the genomic scale

The paper models the genetic footprint of fluctuating balancing selection and shows it increases diversity near selected sites but reduces it elsewhere, potentially lowering genome-wide diversity.

VolcanoFinder: genomic scans for adaptive introgression

VolcanoFinder detects adaptive introgression using polymorphism data from a single population, identifying volcano-shaped patterns of increased variability around beneficial alleles.

The limits to parapatric speciation 3: Evolution of strong reproductive isolation in presence of gene flow despite limited ecological differentiation.

The paper investigates how strong reproductive isolation can evolve with gene flow and limited ecological differentiation using models of local adaptation and Dobzhansky-Muller incompatibilities.

Polygenic Adaptation: From sweeps to subtle frequency shifts

This paper develops a theoretical framework to predict the adaptive architecture of a polygenic trait based on mutation rates, population size, and genetic redundancy, showing that adaptation can occur via sweeps or small allele frequency shifts depending on parameters.

Evolutionary dynamics in structured populations under strong population genetic forces

This study uses modeling to show how migration and selection interact to create non-monotonic FST patterns in adapting populations and estimates high migration rates in a Simian-HIV population.

The influence of fluctuating population densities on evolutionary dynamics

This study examines how fluctuating population densities affect evolutionary dynamics in spatially structured populations, showing that ecological feedback can reduce the equilibrium frequency of locally adapted types.

Spatial soft sweeps: patterns of adaptation in populations with long-range dispersal

This study examines spatial patterns of soft sweeps in populations with long-range dispersal, showing how mutant clones form core-halo structures and affect genetic diversity and future adaptation.

Soft sweeps and beyond: Understanding the patterns and probabilities of selection footprints under rapid adaptation

The paper examines patterns and probabilities of selection footprints under rapid adaptation, showing that soft sweeps are frequent but complex footprints remain inadequately explained by current models.

Bounds to Parapatric Speciation: A Dobzhansky-Muller incompatibility model involving autosomes, X chromosomes and mitochondria

The paper models the stability of Dobzhansky-Muller incompatibilities (DMIs) across autosomes, X chromosomes, and mitochondria, showing X-linkage can increase migration tolerance under dosage compensation and male-biased migration.