Cancer BiologybioRxiv
Widespread perturbation of ETS factor binding sites in cancer
S. C. Pro, H. Hook, D. Bray…·J. I. F. Bass
The paper identifies 2,555 driver non-coding variants in cancer promoters using a TF-aware burden test, showing widespread disruption of ETS factor binding.
DOI 10.1038/s41467-023-36535-8