Author

M. Yin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Evolutionary Biology· 2 Immunology· 2 Microbiology· 2 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Organism:human· 6 Research Focus:differential expression· 5 Approach:statistical model· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:drug response / drug discovery· 3 Research Focus:gene regulatory network inference· 3

Frequent Co-Authors

Y. Zhang· 4 shared L. Liu· 3 shared D. D. Ho· 2 shared G. Cerutti· 2 shared J. Cao· 2 shared L. Shapiro· 2 shared L. Wang· 2 shared M. Zhang· 2 shared

Activity by Year

2017-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersPhysiology

Y. Zhang

Mutual co-authors in cluster

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15 papers

Recent·Most cited

Force-Enhanced Sensitive Detection of New DNA-Interactive Agents from Microorganisms at the Single-Molecule Level

T. Liu, T. Cai, J. Huo, H. Liu, A. Li, M. Yin, Y. Mei, Y. Zhou, S. Fan, Y. Lu, L. Wan, H. You, X. Cai

This paper introduces a single-molecule stretching assay to detect DNA-intercalating agents from microorganisms, identifying two strains and three compounds with anti-cancer activity.

bioRxiv · Apr 22, 2024 · PreprintBiophysics

Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics

Y. Liu, M. Yin, X. Mao, S. Wu, S. Wei, S. Heng, Y. Yang, J. Huang, Z. Guo, C. Li, C. Ji, L. Hu, W. Liu, L.-j. Zhang

This study uses single-cell transcriptomics to identify cell type-specific immune responses in a mouse model of allergic contact dermatitis, highlighting the role of dermal fibroblasts in type-1 inflammation.

bioRxiv · Jan 16, 2024Immunology

Chemotherapeutic regulation of the ROS/MondoA-dependent TXNIP/GDF15 axis; and derivation of a new organoid metric as a predictive biomarker

J. Deng, T. Pan, Y. Hong, Z. Liu, X. Zhou, Z. An, L. Li, G. Alfano, G. Li, L. Dolcetti, R. Evans, J. M. Vicencio, P. Vlckova, Y. Chen, J. Monypenny, , T. Ng

The paper identifies chemotherapy-induced TXNIP as a negative regulator of GDF15 in CRC, showing its potential as a prognostic biomarker through organoid models.

bioRxiv · Aug 10, 2023 · PreprintCancer Biology

Not just with the natives, but phylogenetic relationship between stages of the invasion process determines invasion success of alien plant species

A. K. Banerjee, F. Hui, X. Liang, F. Tan, J. Wang, Y. Lin, M. Yin, H. Peng, W. Guo, N. Zhang, Y. Huang

The paper tests Darwin's hypotheses on alien plant invasion success by analyzing phylogenetic relationships across invasion stages and environmental contexts.

bioRxiv · Oct 12, 2022 · PreprintEcology

Widespread perturbation of ETS factor binding sites in cancer

S. C. Pro, H. Hook, D. Bray, D. Berenzy, D. Moyer, M. Yin, A. T. Labadorf, R. Tewhey, T. Siggers, J. I. F. Bass

The paper identifies 2,555 driver non-coding variants in cancer promoters using a TF-aware burden test, showing widespread disruption of ETS factor binding.

bioRxiv · Aug 10, 2022Cancer Biology

Why is Babesia not killed by artemisinin like Plasmodium?

W. Si, C. Fang, C. Liu, M. Yin, W. Xu, Y. Li, X. Yan, Y. Shen, J. Cao, J. Sun

This study compares Babesia and Plasmodium genomes and gene expression to explain why Babesia is not killed by artemisinin, finding differences in haem synthesis, iron utilization, and gene expression.

bioRxiv · Aug 1, 2022Evolutionary Biology

A quadratic analytical solution of root pressure generation provides insights about bamboo and other species

D. Yang, X. Wang, M. Yin, Y. Zhang, G. Peng, M. T. Tyree

The paper derives an analytical solution for root pressure and applies it to a 7-meter bamboo shoot's hydraulic architecture.

bioRxiv · Dec 21, 2021 · PreprintPhysiology

Isolation and comparative analysis of antibodies that broadly neutralize sarbecoviruses

L. Liu, S. Iketani, Y. Guo, R. Casner, E. Reddem, M. S. Nair, J. Yu, J. Chan, M. Wang, G. Cerutti, Z. Li, C. Castagna, L. Corredor, H. Chu, S. Yuan, , D. D. Ho

The paper identifies a human monoclonal antibody that neutralizes all tested sarbecoviruses and describes a new antibody class with potential for pandemic preparedness.

bioRxiv · Dec 11, 2021 · PreprintMicrobiology

Genome-wide analysis tracks the emergence of intraspecific polyploids in Phragmites australis

C. Wang, L. Liu, M. Yin, F. Eller, H. Brix, T. Wang, J. Salojarvi, W. Guo

This study uses genome-wide analysis to track polyploid emergence in Phragmites australis, identifying multiple lineages and ploidy levels with genomic conflicts.

bioRxiv · Sep 5, 2021 · PreprintEvolutionary Biology

Integrative molecular and clinical profiling of acral melanoma identifies LZTR1 as a key tumor promoter and therapeutic target

F. Farshidfar, C. Peng, C. Levovitz, J. Knight, A. Bacchiocchi, J. Su, K. Rhrissorrakrai, M. Yin, M. Sznol, S. Ariyan, J. Clune, K. Olino, L. Parida, J. Nikolaus, M. Zhang, , R. M. Halaban

bioRxiv · Apr 20, 2021 · PreprintCancer Biology

Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution

L. Wang, J. Li, S. He, H. Chen, S. He, M. Yin, D. Zou, J. Xu, S. Chen, T. Luo, X. Yu, J. BEI, Z. Guo, X. He

The paper analyzes single-cell transcriptomes during liver transplantation to understand ischemia-reperfusion injury and identifies a protective role for TNIP3 in Kupffer cells.

bioRxiv · Jan 10, 2021Cell Biology

CECR2 Drives Breast Cancer Metastasis by Suppressing Macrophage Inflammatory Responses

M. Zhang, Z. Liu, K. Aoshima, Y. Zhang, Y. An, A. Aoshima, L. H. Chan, S. Lang, H. Sun, Z. Tang, S. Rutter, C. J. Booth, V. Bossuyt, X. Chen, J. Morrow, , Q. Yan

This study identifies CECR2 as a driver of breast cancer metastasis by suppressing macrophage inflammatory responses, offering a therapeutic target for metastatic disease.

bioRxiv · Sep 10, 2020Cancer Biology

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

T. Zhou, I.-T. Teng, A. S. Olia, G. Cerutti, J. Gorman, A. Nazzari, W. Shi, Y. Tsybovsky, L. Wang, S. Wang, B. Zhang, Y. Zhang, P. S. Katsamba, Y. Petrova, B. B. Banach, , P. D. Kwong

The paper develops biotin-labeled SARS-CoV-2 spike molecular probes using structure-based design and purification methods, achieving high yields and enabling antibody characterization.

bioRxiv · Jun 22, 2020Immunology

3D Printed Microheater Sensor-Integrated, Drug-Encapsulated Microneedle Patch System for Pain Management

M. Yin, L. Xiao, Q. Liu, S.-Y. Kwon, Y. Zhang, P. R. Sharma, L. Jin, X. J. Li, B. Xu

This paper presents a 3D printed microheater integrated microneedle patch system for controlled drug delivery, demonstrating its integration with wearable electronics for pain management.

bioRxiv · Oct 1, 2019Bioengineering

Dominance of ST131 Escherichia coli carrying blaCTX-M in patients with bloodstream infections caused by cephalosporin-resistant strains in Australia, New Zealand and Singapore: whole genome analysis of isolates from a randomised trial

P. Harris, N. Ben Zakour, L. W. Roberts, A. M. Wailan, H. M. Zowawi, P. A. Tambyah, D. C. Lye, R. Jureen, T. H. Lee, E. Izharuddin, M. Yin, D. Looke, N. Runnegar, B. Rogers, H. Bhally, , D. L. Paterson

The paper characterizes multidrug-resistant Escherichia coli from bloodstream infections in Australia, New Zealand, and Singapore, finding ST131 dominates with blaCTX-M ESBLs, particularly blaCTX-M-15.

bioRxiv · Aug 29, 2017Microbiology