Methylthioadenosine reduces host inflammatory response by suppressing Salmonella virulence
J. S. Bourgeois, D. Zhou, T. L. M. Thurston, J. J. Gilchrist, D. Ko
This study shows that methylthioadenosine (MTA) reduces Salmonella virulence by suppressing flagellar and SPI-1 networks, leading to decreased motility, pyroptosis, and inflammation in mice.
bioRxiv · Mar 23, 2018Microbiology