Author

J. J. H. Elder

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Biochemistry· 1

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Research Focus:chromatin & epigenetic regulation· 1 Approach:statistical model· 1

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C. W. Carter· 1 shared G. Q. Tang· 1 shared J. Douglas· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiochemistry

C. W. Carter

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1 paper

Recent·Most cited

BiochemistrybioRxivApr 26, 2023

Domain Acquisition by Class I Aminoacyl-tRNA Synthetase Urzymes Coordinated the Catalytic Functions of HVGH and KMSKS Motifs

G. Q. Tang, J. J. H. Elder, J. Douglas, C. W. Carter

This study examines the energetic coupling of catalytic motifs in LeuRS and its urzyme ancestor, showing how domain acquisition enhances transition-state stabilization.

DOI 10.1093/nar/gkad590

statistical modelchromatin & epigenetic regulation

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