Author

G. Q. Tang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

c. W. carter· 2 shared J. Douglas· 2 shared J. J. H. Elder· 1 shared L. Betts· 1 shared P. R. Wills· 1 shared R. Bouckaert· 1 shared S. K. Patra· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersEvolutionary Biology

c. W. carter

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2 papers

Recent·Most cited

Genomic database furnishes a spontaneous example of a functional Class II glycyl-tRNA synthetase urzyme

S. K. Patra, J. Douglas, P. R. Wills, R. Bouckaert, L. Betts, G. Q. Tang, c. W. carter

The paper identifies a functional urzyme, GlyCA, from an arctic fox genome that exhibits enhanced catalytic activity compared to known urzymes, supporting the idea that urzymes represent ancestral catalytic activities in genetic coding.

bioRxiv · Jan 11, 2024 · PreprintEvolutionary Biology

Domain Acquisition by Class I Aminoacyl-tRNA Synthetase Urzymes Coordinated the Catalytic Functions of HVGH and KMSKS Motifs

G. Q. Tang, J. J. H. Elder, J. Douglas, C. W. Carter

This study examines the energetic coupling of catalytic motifs in LeuRS and its urzyme ancestor, showing how domain acquisition enhances transition-state stabilization.

bioRxiv · Apr 26, 2023Biochemistry