Cancer BiologybioRxivPreprint
Hematopoietic Stem Cells Undergo Differentiation State Reprogramming to Overcome Venetoclax Sensitivity in Patients with Myelodysplastic Syndromes
J. J. Rodriguez Sevilla, I. Ganan-Gomez, F. Ma…·S. Colla
This study shows MDS hematopoietic stem cells reprogram their differentiation state to bypass venetoclax sensitivity through genetic mutations and transcriptional changes.
DOI 10.1101/2023.09.25.559439