Broadly-reactive IgG responses to heterologous H5 prime-boost influenza vaccination are shaped by antigenic relatedness to priming strains
J. Wang, D. Li, S. Perry, S. P. Hilchey, A. Wiltse, J. J. Treanor, M. Y. Sangster, M. S. Zand
The paper examines how prior H5 exposure influences IgG responses to H5 vaccination, finding that antibody breadth and strength correlate with antigenic distance to priming strains.
bioRxiv · Apr 9, 2021Immunology