Beyond self-resistance: ABCF ATPase LmrC is a signal-transducing component of an antibiotic-driven signaling cascade hastening the onset of lincomycin biosynthesis
M. Koberska, L. Vesela, V. Vimberg, J. Lenart, J. Vesela, Z. Kamenik, J. Janata, G. Balikova Novotna
The paper identifies LmrC, an ABCF ATPase, as a signal-transducing component that accelerates lincomycin biosynthesis in response to ribosome-targeting antibiotics through a ribosome-mediated signaling cascade.
bioRxiv · Oct 16, 2020Microbiology