Author

J. Joshua Smith

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aron BercziD· 1 shared Chao WuiD· 1 shared David LukacsovichiD· 1 shared Hanchen Huang· 1 shared Janet A. AlvareziD· 1 shared Lily WangiD· 1 shared Min Jung KimiD· 1 shared Paul Bernard RomesseriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

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1 paper

Recent·Most cited

Integrating Tumor and Organoid DNA Methylation Profiles Reveals Robust Predictors of Chemotherapy Response in Rectal Cancer

David Lukacsovich, Wini V. Zambare, Chao Wu, Hanchen Huang, Wei Zhang, Min Jung Kim, Janet A. Alvarez, Aron Bercz, Philip B. Paty, Paul Bernard Romesser, Lily Wang, J. Joshua Smith, Xi Chen

This study integrates DNA methylation profiles from tumors and organoids to identify CpGs predictive of chemotherapy response in rectal cancer, finding a methylation risk score significantly predicts progression-free survival.

medRxiv · Feb 28, 2025 · PreprintGenetic & Genomic Medicine