Genetic & Genomic MedicinemedRxivPreprint
Integrating Tumor and Organoid DNA Methylation Profiles Reveals Robust Predictors of Chemotherapy Response in Rectal Cancer
David Lukacsovich, Wini V. Zambare, Chao Wu…·Xi Chen
This study integrates DNA methylation profiles from tumors and organoids to identify CpGs predictive of chemotherapy response in rectal cancer, finding a methylation risk score significantly predicts progression-free survival.
DOI 10.1101/2025.02.28.25322951