Self-replication of Abeta42 aggregates occurs on small and isolated fibril sites
S. Curk, J. Krausser, G. Meisl, D. Frenkel, S. Linse, T. C. T. Michaels, T. P. J. Knowles, A. Saric
The paper investigates A{beta}42 fibril self-replication using statistical mechanics and modeling, finding replication occurs on isolated small catalytic sites on the fibril surface.
bioRxiv · Jul 5, 2023 · PreprintBiophysics