Characterizing Human Mesenchymal Stromal Cells Immune Modulatory Potency Using Targeted Lipidomic Profiling of Sphingolipids
S. A. DeVeaux, M. E. Ogle, S. Vyshnya, N. F. Chiappa, B. Leitmann, R. Rudy, A. Day, L. J. Mortensen, J. Kurtzberg, K. Roy, E. Botchwey
This study uses lipidomic profiling to characterize sphingolipids in MSCs from different sources and identifies sex- and stimulation-dependent differences in ceramide levels linked to immune modulatory potency.
bioRxiv · Jun 1, 2021Bioengineering