Author

J. L. Cooperstone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 3 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:metabolomics· 4 Organism:plant (other)· 4 Approach:statistical model· 4 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

D. M. Francis· 3 shared M. P. Dzakovich· 3 shared E. A. Bilbrey· 2 shared M. L. Goggans· 2 shared C. D. Quiroz-Moreno· 1 shared D. Doud Miller· 1 shared E. Hatzakis· 1 shared J. Fresnedo Ramirez· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

D. M. Francis

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Transcriptomics and Metabolomics Reveal Tomato Consumption Alters Hepatic Xenobiotic Metabolism and Induces Steroidal Alkaloid Metabolite Accumulation in Mice

M. P. Dzakovich, M. L. Goggans, J. M. Thomas-Ahner, N. E. Moran, S. K. Clinton, D. M. Francis, J. L. Cooperstone

This study shows tomato consumption changes mouse liver gene expression and metabolite profiles, particularly affecting xenobiotic metabolism and steroidal alkaloid accumulation.

bioRxiv · Apr 18, 2023Biochemistry

Short term tomato consumption alters the pig gut microbiome towards a more favorable profile

M. L. Goggans, E. A. Bilbrey, C. D. Quiroz-Moreno, D. M. Francis, S. K. Jacobi, J. Kovac, J. L. Cooperstone

This study shows that short-term tomato consumption in piglets increases the ratio of Bacteroidota to Bacillota and alpha-diversity, suggesting a beneficial shift in the gut microbiome.

bioRxiv · May 13, 2022Microbiology

Integrating genomics and multi-platform metabolomics enables metabolite QTL detection in breeding-relevant apple germplasm

E. A. Bilbrey, K. Williamson, E. Hatzakis, D. Doud Miller, J. Fresnedo Ramirez, J. L. Cooperstone

The paper develops a high-throughput integration strategy for genomic and multi-platform metabolomics data to detect metabolite QTL in apple germplasm, identifying novel candidate gene-metabolite relationships.

New Phytologist · Oct 4, 2021Peer-reviewedPlant Biology

Biosynthesis of Steroidal Alkaloids Are Coordinately Regulated and Differ Among Tomatoes in the Red-Fruited Clade

M. P. Dzakovich, D. M. Francis, J. L. Cooperstone

The paper quantifies steroidal alkaloid diversity and identifies QTLs in tomato populations, finding coordinated biosynthesis and species-dependent correlations.

bioRxiv · Jan 6, 2021Plant Biology

A High-Throughput Extraction and Analysis Method for Steroidal Glycoalkaloids in Tomato

M. P. Dzakovich, J. L. Hartman, J. L. Cooperstone

The paper develops and validates a high-throughput method for extracting and quantifying steroidal glycoalkaloids in tomato and tomato-based products.

bioRxiv · Dec 23, 2019Plant Biology