Author

M. L. Goggans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:metabolomics· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

D. M. Francis· 3 shared J. L. Cooperstone· 2 shared M. P. Dzakovich· 2 shared S. K. Jacobi· 2 shared C. D. Quiroz-Moreno· 1 shared E. A. Bilbrey· 1 shared J. Cooperstone· 1 shared J. Kovac· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersPharmacology & Toxicology

D. M. Francis

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3 papers

Recent·Most cited

Discovery of steroidal alkaloid metabolites and their accumulation in pigs after short-term tomato consumption

M. J. Sholola, M. L. Goggans, M. P. Dzakovich, D. M. Francis, S. K. Jacobi, J. Cooperstone

This study identifies and quantifies steroidal alkaloid metabolites in pig plasma after short-term tomato consumption, revealing their concentrations and metabolic phases.

bioRxiv · Feb 5, 2024Pharmacology & Toxicology

Transcriptomics and Metabolomics Reveal Tomato Consumption Alters Hepatic Xenobiotic Metabolism and Induces Steroidal Alkaloid Metabolite Accumulation in Mice

M. P. Dzakovich, M. L. Goggans, J. M. Thomas-Ahner, N. E. Moran, S. K. Clinton, D. M. Francis, J. L. Cooperstone

This study shows tomato consumption changes mouse liver gene expression and metabolite profiles, particularly affecting xenobiotic metabolism and steroidal alkaloid accumulation.

bioRxiv · Apr 18, 2023Biochemistry

Short term tomato consumption alters the pig gut microbiome towards a more favorable profile

M. L. Goggans, E. A. Bilbrey, C. D. Quiroz-Moreno, D. M. Francis, S. K. Jacobi, J. Kovac, J. L. Cooperstone

This study shows that short-term tomato consumption in piglets increases the ratio of Bacteroidota to Bacillota and alpha-diversity, suggesting a beneficial shift in the gut microbiome.

bioRxiv · May 13, 2022Microbiology