Novel substrate prediction for the TAM family of RTKs using phosphoproteomics and structure-based modeling
N. Widstrom, G. Andrianov, J. L. Heier, C. J. Heier, J. L. Karanicolas, L. L. Parker
This paper designs synthetic peptide substrates for TAM family kinases using phosphoproteomics and AlphaFold2, showing that predicted interactions correlate with biochemical validation.
bioRxiv · Sep 1, 2023Biochemistry