DFNA5-mediated pyroptosis is a driver for venetoclax and azacytidine synergy in myeloid leukemia
A. N. Mahesh, J. Lai XIN-Yi, M. Tng Jia Lin, W. Lin, J. C. Wan, J. Yoon, K. Chen, S. Bhatt
This study shows that DFNA5-mediated pyroptosis contributes to the synergy between venetoclax and azacytidine in myeloid leukemia, beyond apoptosis.
bioRxiv · Nov 17, 2023 · PreprintCancer Biology