Broad spectrum capture of clinical pathogens using engineered Fc-Mannose-Binding Lectin (FcMBL) enhanced by antibiotic treatment
B. T. Seiler, M. Cartwright, A. L. M. Dinis, S. Duffy, P. Lombardo, D. Cartwright, E. H. Super, J. Lanzaro, K. Dugas, M. Super, D. E. Ingber
This study demonstrates that FcMBL binds to 86% of pathogen isolates and 90% of pathogen species, including bacteria, fungi, viruses, and parasites, and antibiotic treatment enhances its binding efficiency.
bioRxiv · Aug 8, 2018Immunology