The Shh/Gli3 gene regulatory network precedes the origin of paired fins and reveals the deep homology between distal fins and digits.
J. Letelier, S. Naranjo, I. Sospedra, J. Lopez-Rios, J. R. Martinez-Morales, N. Shubin, J. L. Gomez-Skarmeta
This study shows that the Shh/Gli3 gene regulatory network controls proliferation in distal fin and limb regions, revealing deep homology between these structures.
bioRxiv · Sep 8, 2020Evolutionary Biology